In a study published in the New England Journal of Medicine,
the popular dietary supplement combination of glucosamine plus
chondroitin sulfate did not provide significant relief from
osteoarthritis pain among all participants. However, a smaller subgroup
of study participants with moderate-to-severe pain showed significant
relief with the combined supplements.
This research was funded by the National Center for Complementary
and Alternative Medicine (NCCAM) and the National Institute of
Arthritis and Musculoskeletal and Skin Diseases (NIAMS), components of
the National Institutes of Health (NIH). Researchers led by
rheumatologist Daniel O. Clegg, M.D., of the University of Utah, School
of Medicine, Salt Lake City, conducted the 4-year study known as the
Glucosamine/chondroitin Arthritis Intervention Trial (GAIT) at 16 sites
across the United States.
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