Atherosclerosis: A type of "hardening of the arteries"
in which cholesterol, fat, and other substances in the blood build up in
the walls of arteries. As the process continues, the arteries to the
heart may narrow, cutting down the flow of oxygen-rich blood and
nutrients to the heart.
Bile Acid Sequestrants: One type of cholesterol-lowering
medication, including cholestyramine and colestipol. The sequestrants
bind with cholesterol-containing bile acids in the intestines and
remove them in bowel movements.
Calories: Units of measurement that represent the amount
of energy the body is able to get from foods. Different nutrients in
foods provide different amounts of calories. Carbohydrates and protein
provide about 4 calories per gram, while fat (bother saturated and
unsaturated) yields about 9 calories per gram.
Carbohydrate: One of the nutrients that supply calories to
the body. Carbohydrates may be simple or complex. Complex
carbohydrates also are called starch and fiber, which come from plants
and can be found in whole-grain breads, cereals, pasta, rice, dried
peas, and beans, corn, lima beans, fruits, and vegetables.
Cholesterol: A soft, waxy substance. The body makes enough
cholesterol to meet its needs. Cholesterol is used in the manufacture
of hormones, bile acid, and vitamin D. It is present in all parts of
the body, including the nervous system, muscle, skin, liver,
intestines, and heart.
- Blood cholesterol - Cholesterol circulating in the
bloodstream. It is made in the liver and absorbed from the food you
eat. The blood carries it for use by all parts of the body. A high
level of blood cholesterol leads to atherosclerosis and an increased
risk of heart disease.
- Dietary cholesterol - Cholesterol in the food you eat.
It is present only in foods of animal origin, not those of plant
origin. Dietary cholesterol, like dietary saturated fat, raises
blood cholesterol, which increases the risk for heart disease.
Estrogen Replacement Therapy (ERT): Treatment with he
hormone estrogen, which has many effects, one of which is cholesterol
lowering. It includes different amounts of estrogen and progestin, two
hormones produced normally by women who have menstrual periods. ERT is
given only to women who have gone through menopause. ERT may help
prevent heart disease by lowering blood cholesterol levels, especially
LDL.
Fat: One of the nutrients that supply calories to the
body. The body needs only small amount of fat. Foods contain different
types of fat, which have different effect on blood cholesterol levels.
These include:
- Total fat - The sum of the saturated, monounsaturated,
and polyunsaturated fats present in food. All foods have a varying
mix of these three types.
- Saturated fat - A type of fat found in greatest amounts
in the skin, whole-milk dairy products, lard, and in some vegetable
oils, including coconut, palm kernel, and palm oils. Saturated fat
raises blood cholesterol more than anything else eaten.
- Unsaturated fat - A type of fat that is usually liquid
at refrigerator temperature. Monounsaturate fat and polyunsaturated
fat are two kinds of unsaturated fat. When used in place of
saturated fat, monunsaturated and polyunsaturated fats help to lower
blood cholesterol levels.
- Monounsaturated fat - An unsaturated fat that is found
in greatest amount in food from plants, including olive and canola
oil.
- Polyunsaturated fat - An unsaturated fat found in
greatest amounts in foods from plants, including safflower,
sunflower, corn, and soybean oils.
Fibric Acid Derivatives: One type of cholesterol-lowering
drug. It includes gemfibrozil. The fibric acids lower triglycerides
and raise HDLs.
HMG CoA Reductase Inhibitors: See "Statins."
Lipids: Fatty substances, including cholesterol and
triglycerides, that are present in blood and body tissues.
Lipoproteins: Protein-coated packages that carry fat and
cholesterol through the bloodstream. Lipoproteins are classified
according to their density.
- High-density lipoprotein (HDL) - Lipoproteins that
contain a small amount of cholesterol and carry cholesterol away
from body cells and tissues to the liver for the excretion from the
body. A low level of HDL increases the risk of heart disease, so the
higher the HDL level, the better. HDL is sometimes called the "good"
cholesterol.
- Low-density lipoprotein (LDL) - Lipoproteins that
contain most of the cholesterol in the blood. LDL, the "bad"
cholesterol, carries cholesterol to the tissues of the body
including the arteries. For this reason, a high level of LDL
increases the risk of heart disease.
Lipoprotein Profile: A test that uses blood from the arm
to measure your total, HDL-, and LDL-cholesterol, and triglyceride
levels. The test requires a fast for 9-12 hours beforehand. Nothing
can be consumed but water, or coffee or tea with no cream or sugar.
Milligram (mg): A unit of weight equal to one-thousandth
of a gram. There are about 28,350 mg in 1 ounce. Dietary cholesterol
is measured in milligrams.
Milligrams/Deciliter (mg/dL): The measure used to express
cholesterol and triglyceride levels in the blood. It stands for the
weight of cholesterol in milligrams in a deciliter of blood. A
deciliter is one-tenth of a liter or about one-tenth of a quart.
Nicontinic Acid: A cholesterol-lowering medicine that
reduces total and LDL-cholesterol and triglyceride levels and also
raises HDL-cholesterol levels. This is the same substance as Niacin or
vitamin B1, but in doses that lower cholesterol, it should only be
used with your doctor's supervision.
Risk Factor: A habit, trait, or condition in a person that
is associated with an increased chance (or risk) for a disease.
Statins: One type of cholesterol-lowering drug that
includes lovastatin, pravastatin, and simvastatin. These drugs lower
LDL levels by limiting the amount of cholesterol the body can make.
Triglycerides: Lipids carried through the bloodstream to
tissues. Most of the body's fat tissue is in the form of
triglycerides, stored for use as energy. Triglycerides are obtained
primarily from fat in foods.